N-T-BUTOXYCARBONYL-(R)-3-AMINO-4,4-DIPHENYL-BUTANOIC ACID - Names and Identifiers
N-T-BUTOXYCARBONYL-(R)-3-AMINO-4,4-DIPHENYL-BUTANOIC ACID - Physico-chemical Properties
Molecular Formula | C21H25NO4
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Molar Mass | 355.43 |
Density | 1.150 |
Storage Condition | 2-8°C |
N-T-BUTOXYCARBONYL-(R)-3-AMINO-4,4-DIPHENYL-BUTANOIC ACID - Risk and Safety
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
N-T-BUTOXYCARBONYL-(R)-3-AMINO-4,4-DIPHENYL-BUTANOIC ACID - Introduction
Boc-(R)-3-Amino-4,4-diphenyl-butyric acid is an organic compound with the following properties:
1. Appearance: colorless crystal or white powder.
2. molecular formula: C23H25NO4.
3. molecular weight: 375.45.
4. Melting point: about 135-140°C.
5. Solubility: Soluble in common organic solvents such as dichloromethane and ethanol.
Boc-(R)-3-Amino-4,4-diphenyl-butyric acid has important applications in organic synthesis, especially in the field of pharmaceutical synthesis. It can be used as a chiral building block for the synthesis of various biologically active molecules. Common applications include drug synthesis, preparation of catalysts, and functionalization of polymers.
The preparation of the compound generally takes the following steps:
1. Synthesis of two benzyl terephthalate: styrene and benzyl alcohol are prepared by condensation reaction under the action of catalyst
2. Hydroxylation reaction: the two benzyl terephthalate and excess sodium hydroxide are reacted at high temperature to generate two (benzyl) terephthalic acid ether
3. synthesis of bath and horst: reaction of terephthalic acid bis (benzyl) ether with ethyl isopropyl amino dicarboxylic acid in toluene to generate Boc-(R)-3-Amino-4,4-diphenyl-butyric acid
Regarding safety information, Boc-(R)-3-Amino-4,4-diphenyl-butyric acid has low toxicity under general operating conditions. However, as a chemical substance, appropriate laboratory safety measures should be taken, including wearing protective glasses and gloves to ensure that the operation is carried out in a well-ventilated environment. During use, please follow the relevant chemical safety procedures and comply with local laws and regulations.
Last Update:2024-04-09 20:45:29